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What is PSA?:

PSA is a protein that is made in the prostate. This substance can be increased in the bloodstream in cancers and in other medical conditions.



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It has also been shown that once a diagnosis of cancer has been made, the higher the PSA the greater the chance that the tumor has spread to lymph nodes and distant areas in the body.


Signs and Symptons

 

 

These include:
Benign conditions such as infections and inflammation of the prostate gland, known as prostatitis (increased level)
Benign prostatic hyperplasia (increased level)
Following sexual activity (increased level)
The use of Propecia (decreased level)
The use of an herb known as saw palmetto, which is used for benign prostatic hypertrophy (decreased level)

It is interesting that the PSA level can also be normal in patients who have prostate cancer.

PSA is usually reported in a special unit called a nanogram. Normal levels of PSA are usually less than 4. Levels that are possibly related to a prostate cancer range between 4 and 10, and those that are highly suspicious for cancer have a PSA greater than 10.

Another PSA test, known as the percent free-PSA, is also being tested to see if it can improve on what the PSA blood test shows. This test determines how much free or unattached PSA is in the blood and how much is "bound" or attached to special molecules. If the percent of free PSA is less than 25% and your PSA is greater than 4, it is believed that this is very suspicious for being due to a prostate cancer.
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