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Patient/Family Information Clinical Brain Mets Treatment

Chemotherapy/Hormones:

In the past, patients were not treated with chemotherapy to control disease in the brain. This is because it was thought that the blood-brain barrier (the protective barrier around the brain) prevented chemotherapy agents from getting directly into the brain tissue. Recently this assumption was found to be false. Now more emphasis is being placed on the use of chemotherapy in an effort to try to reduce some of the symptoms seen from spread of cancers to the brain.


In some cases hormone treatment, especially for breast and prostate cancers, may have a dramatic relief of any symptoms that are occurring. These hormone treatments act by trying to block the cancer cells from growing. This is done by not allowing certain naturally occurring hormones from acting on these cells. The hormones can have their own special side effects that can include the loss of desire to have sex, hot flashes, fatigue and an increased risk of developing blood clots and developing other cancers. Please ask your doctor about all the possible side effects that may occur if you are receiving any hormone treatments.

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